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Compare scores, permissions, risks, and fit in one decision-focused table.

DimensionChEMBL MCP ServerUnofficial MCP server providing advanced access to the ChEMBL chemical databaseSupabase MCP ServerConnect Supabase to your AI assistants
FMRS75 / 100 · B74 / 100 · B
Reliability12 / 2010 / 20
Security and permissions16 / 2015 / 20
Maintenance14 / 2018 / 20
Documentation18 / 2017 / 20
Setup experience15 / 2014 / 20
Best for
  • Drug discovery and computational chemistry researchers
  • Bioinformatics teams needing ChEMBL data through AI assistants
  • Developers comfortable with Node.js or Docker
  • Developers and teams using Supabase
  • Users wanting to integrate AI into database workflows
Not for
  • Production settings requiring official ChEMBL support (this is unofficial)
  • Users without a Node.js or Docker environment
  • General database tasks unrelated to ChEMBL
  • Users not using Supabase
  • Scenarios requiring fully local and cloud-free operations (CLI has limited features)
Required permissions
  • Outbound network access to https://www.ebi.ac.uk/chembl/api/data
  • Read-only access to public API data; no authentication credentials required
  • Requires Supabase access token (SUPABASE_ACCESS_TOKEN)
  • May require OAuth 2.1 authorization (remote)
  • Read/write by default; read-only mode available (--read-only)
Risks and side effects
  • Unofficial project with license marked NOASSERTION (README claims MIT); verify licensing yourself
  • Data accuracy depends on the ChEMBL REST API and the server's parsing may contain defects
  • 30-second request timeouts may constrain large batch queries
  • README inconsistency on tool count (22 vs 27) raises documentation reliability concerns
  • LLM may execute destructive operations such as dropping tables or deleting data
  • Token leakage could lead to unauthorized access
  • Remote server may log requests, posing privacy concerns
Supported clientsClaude DesktopClaude Desktop, Cursor, Windsurf
Tools270