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DimensionChroma MCP ServerModel Context Protocol server for Chroma, providing database capabilities for AI models.ChEMBL MCP ServerUnofficial MCP server providing advanced access to the ChEMBL chemical database
FMRS48 / 100 · D75 / 100 · B
Reliability8 / 2012 / 20
Security and permissions8 / 2016 / 20
Maintenance10 / 2014 / 20
Documentation10 / 2018 / 20
Setup experience12 / 2015 / 20
Best for
  • Vector database scenarios that need integration with MCP-compatible clients like Claude.
  • Developers and teams who want to self-host Chroma and unify APIs.
  • AI applications that require persistent or cloud-hosted vector storage.
  • Drug discovery and computational chemistry researchers
  • Bioinformatics teams needing ChEMBL data through AI assistants
  • Developers comfortable with Node.js or Docker
Not for
  • Not suitable for non-vector database use cases.
  • Not for applications needing relational queries or complex transactions.
  • Not ideal for scenarios with high data privacy requirements that can't tolerate external API calls (when using external embedding functions).
  • Production settings requiring official ChEMBL support (this is unofficial)
  • Users without a Node.js or Docker environment
  • General database tasks unrelated to ChEMBL
Required permissions
  • File system access (for persistent client) to store data.
  • Network access (for HTTP or cloud clients) to connect to remote Chroma instances or external embedding APIs.
  • API keys in environment variables or config files (e.g., Cohere, OpenAI) to call external embedding models.
  • Outbound network access to https://www.ebi.ac.uk/chembl/api/data
  • Read-only access to public API data; no authentication credentials required
Risks and side effects
  • External embedding APIs may send data to third-party services, posing data leakage risks.
  • Self-hosted HTTP clients without proper authentication may expose sensitive data.
  • Persistent clients require write permissions and backup for the data directory.
  • Unofficial project with license marked NOASSERTION (README claims MIT); verify licensing yourself
  • Data accuracy depends on the ChEMBL REST API and the server's parsing may contain defects
  • 30-second request timeouts may constrain large batch queries
  • README inconsistency on tool count (22 vs 27) raises documentation reliability concerns
Supported clientsClaude DesktopClaude Desktop
Tools1227