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Compare scores, permissions, risks, and fit in one decision-focused table.

DimensionCouchbase MCP ServerLet AI agents securely connect to and work with data in Couchbase clustersChEMBL MCP ServerUnofficial MCP server providing advanced access to the ChEMBL chemical database
FMRS72 / 100 · B75 / 100 · B
Reliability11 / 2012 / 20
Security and permissions16 / 2016 / 20
Maintenance13 / 2014 / 20
Documentation18 / 2018 / 20
Setup experience14 / 2015 / 20
Best for
  • Developers and data teams who want safe AI access to Couchbase data in mainstream MCP clients (Claude Desktop, Cursor, Windsurf, VS Code, JetBrains IDEs)
  • Teams already using Couchbase (Capella or self-managed) who want LLM-assisted querying and analysis
  • Drug discovery and computational chemistry researchers
  • Bioinformatics teams needing ChEMBL data through AI assistants
  • Developers comfortable with Node.js or Docker
Not for
  • Unattended write access to production databases without risk assessment (read-only mode blocks writes by default)
  • Users not running Couchbase or without a running cluster
  • Those needing official support-portal assistance (community-maintained; GitHub only)
  • Production settings requiring official ChEMBL support (this is unofficial)
  • Users without a Node.js or Docker environment
  • General database tasks unrelated to ChEMBL
Required permissions
  • Couchbase connection string plus username/password for basic auth, or client certificate and key paths for mTLS, via environment variables or CLI arguments
  • CA root certificate path for TLS with self-signed/untrusted certificates on non-Capella clusters
  • Database user needs RBAC permissions to access at least one bucket — RBAC is the authoritative security control
  • Outbound network access to https://www.ebi.ac.uk/chembl/api/data
  • Read-only access to public API data; no authentication credentials required
Risks and side effects
  • CB_MCP_READ_ONLY_MODE defaults to true, disabling all writes; when false, the LLM can modify/delete documents, scopes, collections, and indexes
  • Disabling tools alone is not sufficient: SQL++ DML can still modify data via run_sql_plus_plus_query; use read-only mode or proper RBAC
  • delete_scope/delete_collection permanently destroy data
  • The HTTP endpoint is unauthenticated unless OAuth is configured
  • LLM outputs may be inaccurate; Couchbase does not review them and users are solely responsible
  • The product automatically collects usage/performance data (e.g., product version, IP address); see the Couchbase Privacy Policy
  • Unofficial project with license marked NOASSERTION (README claims MIT); verify licensing yourself
  • Data accuracy depends on the ChEMBL REST API and the server's parsing may contain defects
  • 30-second request timeouts may constrain large batch queries
  • README inconsistency on tool count (22 vs 27) raises documentation reliability concerns
Supported clientsClaude Desktop, Cursor, Windsurf Editor, VS Code, JetBrains IDEsClaude Desktop
Tools3327