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Compare scores, permissions, risks, and fit in one decision-focused table.

DimensionMySQL MCP ServerQuery MySQL databases through MCP with read-only defaults.ChEMBL MCP ServerUnofficial MCP server providing advanced access to the ChEMBL chemical database
FMRS50 / 100 · D75 / 100 · B
Reliability8 / 2012 / 20
Security and permissions10 / 2016 / 20
Maintenance9 / 2014 / 20
Documentation11 / 2018 / 20
Setup experience12 / 2015 / 20
Best for
  • Developers and data teams that need AI-assisted MySQL schema inspection or querying
  • Workflows that prefer read-only database access by default
  • Deployments requiring SSH, SSL/TLS, or PII-redaction capabilities
  • Drug discovery and computational chemistry researchers
  • Bioinformatics teams needing ChEMBL data through AI assistants
  • Developers comfortable with Node.js or Docker
Not for
  • Environments that do not use MySQL
  • Workflows requiring write access by default without explicit permission configuration
  • Environments unable to provide suitable database credentials or network connectivity
  • Production settings requiring official ChEMBL support (this is unofficial)
  • Users without a Node.js or Docker environment
  • General database tasks unrelated to ChEMBL
Required permissions
  • Requires configuration for the MySQL host, port, username, password, and database name
  • The database user needs privileges matching the intended queries and any enabled write operations
  • Remote database access may require SSH tunnel configuration
  • When write flags are enabled, the server can perform the corresponding insert, update, or delete operations
  • Outbound network access to https://www.ebi.ac.uk/chembl/api/data
  • Read-only access to public API data; no authentication credentials required
Risks and side effects
  • Although read-only by default, enabled write flags can modify or delete data
  • Database credentials are supplied through environment variables and should be protected
  • SQL queries may expose sensitive data; PII redaction can help reduce exposure
  • Misconfigured database privileges, SSL/TLS, or remote access may broaden data exposure
  • Unofficial project with license marked NOASSERTION (README claims MIT); verify licensing yourself
  • Data accuracy depends on the ChEMBL REST API and the server's parsing may contain defects
  • 30-second request timeouts may constrain large batch queries
  • README inconsistency on tool count (22 vs 27) raises documentation reliability concerns
Supported clientsClaude Desktop, Claude CodeClaude Desktop
Tools127