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Compare scores, permissions, risks, and fit in one decision-focused table.

DimensionMySQL MCP ServerA read-only MySQL MCP server for querying databases through Claude Desktop.MCP ClickHouseConnect ClickHouse to your AI assistantsChEMBL MCP ServerUnofficial MCP server providing advanced access to the ChEMBL chemical database
FMRS53 / 100 · D79 / 100 · B75 / 100 · B
Reliability9 / 2012 / 2012 / 20
Security and permissions8 / 2018 / 2016 / 20
Maintenance9 / 2017 / 2014 / 20
Documentation14 / 2017 / 2018 / 20
Setup experience13 / 2015 / 2015 / 20
Best for
  • Data analysts and developers who want to query read-only MySQL data using natural language
  • Claude Desktop users who need to interact with local MySQL databases seamlessly
  • Teams that need to query MySQL without directly writing SQL
  • Teams already using ClickHouse who want AI assistants to access data directly.
  • Scenarios requiring fast, read-only data queries and schema exploration.
  • Drug discovery and computational chemistry researchers
  • Bioinformatics teams needing ChEMBL data through AI assistants
  • Developers comfortable with Node.js or Docker
Not for
  • Applications that require write or modify operations on the database
  • Applications that need to connect to non-MySQL databases (e.g., PostgreSQL)
  • Production environments without additional security measures and a dedicated read-only user
  • Scenarios requiring write access to the database without explicit opt-in.
  • Production environments with stringent security requirements that avoid default permission settings.
  • Production settings requiring official ChEMBL support (this is unofficial)
  • Users without a Node.js or Docker environment
  • General database tasks unrelated to ChEMBL
Required permissions
  • Requires Node.js v16 or higher
  • Requires a MySQL database server
  • Requires Claude Desktop or Claude Code
  • Requires database credentials (via environment variables or connection string)
  • Grants only SELECT operations if credentials are limited, but if broad credentials are used, read access to all data is possible
  • Requires read-only access to ClickHouse database (default).
  • Optional: write access via CLICKHOUSE_ALLOW_WRITE_ACCESS.
  • Optional: destructive operations via CLICKHOUSE_ALLOW_DROP.
  • Outbound network access to https://www.ebi.ac.uk/chembl/api/data
  • Read-only access to public API data; no authentication credentials required
Risks and side effects
  • Security may be misleading: the server only blocks non-SELECT statements, but if the provided credentials have write permissions, data could be modified; use a dedicated read-only user
  • Data privacy: database credentials are stored in environment variables, accessible to other processes on the same system
  • Network exposure: if the MySQL server is exposed, unauthorized access is possible; ensure network security
  • Resource usage: complex queries may consume significant resources; monitor query performance
  • If write access is enabled, AI might make unintended modifications.
  • If DROP access is enabled, data deletion could occur accidentally.
  • Credentials may be exposed via environment variables.
  • Unofficial project with license marked NOASSERTION (README claims MIT); verify licensing yourself
  • Data accuracy depends on the ChEMBL REST API and the server's parsing may contain defects
  • 30-second request timeouts may constrain large batch queries
  • README inconsistency on tool count (22 vs 27) raises documentation reliability concerns
Supported clientsClaude DesktopClaude DesktopClaude Desktop
Tools3427